ABSTRACT
Objective To explore the effects of music therapy and massage on the quality of newborn hearing screening. Methods One hundred and twenty neonates were equally divided according to their registration number: those with even numbers in the experiment group and those with odd number in the control one. Both groups were treated with music therapy. In the experiment group, massage was added by specially trained nurses on the basis of music therapy. The two groups were compared in terms of neonatal hearing test and screening results. Result In the experiment group, the excellence rate of neonatal hearing test and the success rate of screening were significantly higher than those of the control group ( P<0 . 05 ) . Conclusion The music therapy and massage in the neonatal hearing screening can improve the quality of newborn hearing screening.
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Objective To observe selective cyclooxygenase-2 (COX-2) inhibitor celecoxib on the cell migration, MMP-9 and VEGF expression of human gastric cancer SGC-7901. Methods In vitro culture of SGC-7901 cells, the cells were divided into blank control group and celecoxib treatment group (different concentrations of celecoxib 25, 50 and 100μmol/L). SGC-7901 cells were treated with celecoxib for 24 h. The effect of celecoxib on cell migration of SGC-7901 was detected by the damage repair experiment. RT-PCR assay was used to detect the effect of celecoxib on MMP-9 mRNA and VEGF mRNA expressions in SGC-7901 cells. Results The migration distance of SGC-7901 cells was decreased with the increased concentration of celecoxib. There were significant differences between medium-dose and high-dose celecoxib groups and the control group. RT-PCR assay showed that MMP-9 mRNA and VEGF mRNA expressions in gastric cancer SGC-7901 were significantly decreased with the increased concentration of celecoxib, and there was a significant difference compared with those of control group (P＜0.05). Conclusion Celecoxib can inhibit migration of human gastric cancer SGC-7901 cells, which may be related to the inhibition of COX-2 downstream of MMP-9 and VEGF expressions.
ABSTRACT
OBJECTIVE@#To explore the treatment effect of selective neurotomy of anterior ethmoid nerve and squeezing operation of inferior turbinate in the treatment of perennial allergic rhinitis (PAR).@*METHOD@#Seventy cases of perennial allergic rhinitis were selected and subjected to selective neurotomy of anterior ethmoid nerve and squeezing operation of inferior turbinate,and the treatment effect was observed by analysis of the the symptoms and signs score of all cases preoperatively and postoperatively.@*RESULT@#The total effective rate were 90.0% at 1 year follow-up.@*CONCLUSION@#Selective neurotomy of anterior ethmoid nerve and squeezing operation of inferior turbinate were effective for the patients with PAR. It is worthy to be popularized for its convent and rare complications.